Dr. Stefan Bluml of Children’s Hospital Los Angeles has determined elevated citrate levels can predict future risk for disease progression for certain types of brain tumors. He is currently exploring mechanisms that might cause the increased levels of citrate. His long-term goal is to be able to exploit our improved understanding of tumor metabolism to design more effective therapies.

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• Apparent Diffusion and Fractional Anisotropy of Diffuse Intrinsic Brain Stem Gliomas
• Elevated citrate in pediatric astrocytomas with malignant progression